SCHEMBL5208982

SCHEMBL5208982

CCOC(=O)c1c[c]n(C)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.47
ALDH1A1 P00352 4/20 0.41
KMT2A Q03164 3/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
GAA P10253 2/20 0.40
KDM4E B2RXH2 3/20 0.39
POLB P06746 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
GABRA2 P47869 1/20 0.38
GABRB2 P47870 1/20 0.38
LMNA P02545 1/20 0.38
JMJD6 Q6NYC1 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
RXFP1 Q9HBX9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8669564 0.75 GABRA2 (0.51) CYP1A2ALDH1A1KMT2AMAPTNPC1
SCHEMBL10817921 0.71 TSHR (0.60) CYP1A2ALDH1A1MAPTNPC1RAB9A
SCHEMBL13860587 0.70 CYP1A2 (0.49) CYP1A2ALDH1A1KMT2AMAPTMEN1
Hydrochloric Acid SCHEMBL28351166 0.70 TSHR (0.59) CYP1A2ALDH1A1KMT2AMAPTMEN1
SCHEMBL11175360 0.70 KMT2A (0.42) CYP1A2KMT2ATSHRJMJD6ADORA3
SCHEMBL1233517 0.70 BAZ2B (0.54) CYP1A2KMT2AMAPTNPC1RAB9A
SCHEMBL1739337 0.69 ALDH1A1 (0.61) CYP1A2ALDH1A1KMT2AMAPTMEN1
SCHEMBL4757861 0.69 CYP1A2 (0.51) CYP1A2ALDH1A1KMT2AMAPTMEN1
SCHEMBL1075020 0.69 CYP1A2 (0.51) CYP1A2ALDH1A1KMT2AMAPTMEN1
SCHEMBL10436784 0.69 KMT2A (0.56) CYP1A2ALDH1A1KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0958292-B1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AG (DE) 2007-01-03 EP disclosed
US-6165944-A 4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2000-12-26 US disclosed
US-6004903-A 2-Anylocyclohexanediones having improved herbicidal properties BASF AKTIENGESELLSCHAFT (DE) 1999-12-21 US disclosed