SCHEMBL8669564

SCHEMBL8669564

CCOC(=O)c1c[c]n(-c2ccccc2)n1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GABRA2 P47869 4/20 0.51
GABRB2 P47870 4/20 0.51
GAA P10253 2/20 0.50
KMT2A Q03164 1/20 0.50
PDE4D Q08499 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
MAPT P10636 4/20 0.49
ALDH1A1 P00352 2/20 0.49
CYP1A2 P05177 1/20 0.47
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TP53 P04637 2/20 0.47
ALOX12 P18054 1/20 0.47
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5208982 0.75 CYP1A2 (0.47) GABRA2GABRB2GAAKMT2ANPC1
SCHEMBL9681520 0.74 NPC1 (0.58) GABRA2GABRB2GAAKMT2APDE4D
SCHEMBL7268 0.72 KMT2A (0.68) GAAKMT2APDE4DMAPTALDH1A1
SCHEMBL23354891 0.72 ALDH1A1 (0.52) GABRA2GABRB2GAAKMT2APDE4D
SCHEMBL3299372 0.72 KMT2A (0.68) GAAKMT2APDE4DMAPTALDH1A1
SCHEMBL6086181 0.71 ALDH1A1 (0.51) GABRA2GABRB2GAAKMT2APDE4D
SCHEMBL28625965 0.71 KMT2A (0.67) GAAKMT2APDE4DMAPTALDH1A1
SCHEMBL28728715 0.71 NPC1 (0.62) GABRA2GABRB2GAAPDE4DNPC1
SCHEMBL22896893 0.70 KMT2A (0.65) GABRA2GABRB2GAAKMT2APDE4D
SCHEMBL2835335 0.70 KMT2A (0.65) GAAKMT2APDE4DMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5789618-A Synthetic method for a halogen-containing condensation product KONICA CORPORATION (JP) 1998-08-04 US claimed