SCHEMBL5209119

SCHEMBL5209119

C=C(C)C(=O)OCCC1CSC(CSCSCC2SCC(CCOC(=O)C(=C)C)S2)S1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
THRB P10828 1/20 0.35
TSHR P16473 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5209288 0.87 ALDH1A1 (0.44) ALDH1A1THRBTSHR
SCHEMBL5210062 0.86 CA1 (0.33) ALDH1A1THRBTSHR
SCHEMBL5204315 0.85 TSHR (0.38) ALDH1A1THRBTSHR
SCHEMBL5211417 0.81 TSHR (0.36) ALDH1A1TSHR
SCHEMBL5212443 0.79 THRB (0.41) ALDH1A1THRBTSHR
SCHEMBL5204398 0.79 ALDH1A1 (0.44) ALDH1A1THRBTSHR
SCHEMBL5213041 0.78
SCHEMBL5212211 0.77 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL5206348 0.77 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL5210140 0.77 ALDH1A1 (0.39) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1388540-B1 ACRYLIC ESTERS AND USE THEREOF MITSUI CHEMICALS INC (JP) 2007-09-05 EP disclosed
US-6835844-B2 Acrylic esters and use thereof MITSUI CHEMICALS, INC. (JP) 2004-12-28 US disclosed
EP-1388540-A1 ACRYLIC ESTERS AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2004-02-11 EP disclosed