Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209940 | 0.84 | ALDH1A1 (0.49) | THRBTSHRALDH1A1 | |
| SCHEMBL5209119 | 0.79 | ALDH1A1 (0.36) | THRBTSHRALDH1A1 | |
| SCHEMBL6861883 | 0.76 | CA1 (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL6667114 | 0.76 | TSHR (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5209492 | 0.76 | TSHR (0.43) | THRBTSHRALDH1A1 | |
| SCHEMBL635021 | 0.74 | ALDH1A1 (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL7050248 | 0.73 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5209862 | 0.72 | ALDH1A1 (0.46) | THRBTSHRALDH1A1 | |
| SCHEMBL5210023 | 0.72 | ALDH1A1 (0.46) | THRBTSHRALDH1A1 | |
| SCHEMBL17111006 | 0.71 | THRB (0.40) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1388540-B1 | ACRYLIC ESTERS AND USE THEREOF | MITSUI CHEMICALS INC (JP) | 2007-09-05 | — | — | EP | disclosed |
| EP-1388540-A1 | ACRYLIC ESTERS AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2004-02-11 | — | — | EP | disclosed |