Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RHOA | P61586 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 1/20 | 0.53 |
| ▸ | VCP | P55072 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209309 | 1.00 | MAPT (0.62) | MAPTMAOBNFE2L2MEN1KMT2A | |
| 3-Nitro-Cinnamic Acid SCHEMBL4179178 | 0.91 | MAPT (0.73) | MAPTMAOBNFE2L2MEN1KMT2A | |
| 3-Nitro-Cinnamic Acid SCHEMBL448381 | 0.91 | MAPT (0.73) | MAPTMAOBNFE2L2MEN1KMT2A | |
| 3-Nitro-Cinnamic Acid SCHEMBL3290556 | 0.91 | MAPT (0.73) | MAPTMAOBNFE2L2MEN1KMT2A | |
| 3-Nitro-Cinnamic Acid SCHEMBL426380 | 0.91 | MAPT (0.73) | MAPTMAOBNFE2L2MEN1KMT2A | |
| 3-Nitro-Cinnamic Acid SCHEMBL29626695 | 0.91 | MAPT (0.73) | MAPTMAOBNFE2L2MEN1KMT2A | |
| 3-Nitro-Cinnamic Acid SCHEMBL7990710 | 0.89 | MAPT (0.71) | MAPTMAOBNFE2L2MEN1KMT2A | |
| 3-Nitro-Cinnamic Acid SCHEMBL7401665 | 0.89 | MAPT (0.71) | MAPTMAOBNFE2L2MEN1KMT2A | |
| 3-Nitro-Cinnamic Acid SCHEMBL27877632 | 0.89 | MAPT (0.71) | MAPTMAOBNFE2L2MEN1KMT2A | |
| 3-Nitro-Cinnamic Acid SCHEMBL7990708 | 0.88 | MAPT (0.69) | MAPTMAOBNFE2L2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040103-B1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-6413947-B1 | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| US-6268354-B1 | Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| US-6172061-B1 | AIDS THERAPY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| US-6166006-A | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-1040103-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999032468-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |