Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | MAOB | P27338 | 1/20 | 0.71 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | FBP1 | P09467 | 1/20 | 0.61 |
| ▸ | VCP | P55072 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.59 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.58 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.58 |
| ▸ | ITGAL | P20701 | 1/20 | 0.58 |
| ▸ | TGM2 | P21980 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Nitro-Cinnamic Acid SCHEMBL426380 | 0.98 | MAPT (0.73) | MAPTMAOBNFE2L2ALDH1A1MEN1 | |
| 3-Nitro-Cinnamic Acid SCHEMBL3290556 | 0.98 | MAPT (0.73) | MAPTMAOBNFE2L2ALDH1A1MEN1 | |
| 3-Nitro-Cinnamic Acid SCHEMBL4179178 | 0.98 | MAPT (0.73) | MAPTMAOBNFE2L2ALDH1A1MEN1 | |
| 3-Nitro-Cinnamic Acid SCHEMBL29626695 | 0.98 | MAPT (0.73) | MAPTMAOBNFE2L2ALDH1A1MEN1 | |
| 3-Nitro-Cinnamic Acid SCHEMBL448381 | 0.98 | MAPT (0.73) | MAPTMAOBNFE2L2ALDH1A1MEN1 | |
| 3-Nitro-Cinnamic Acid SCHEMBL27877632 | 0.97 | MAPT (0.71) | MAPTMAOBNFE2L2ALDH1A1MEN1 | |
| 3-Nitro-Cinnamic Acid SCHEMBL7401665 | 0.97 | MAPT (0.71) | MAPTMAOBNFE2L2ALDH1A1MEN1 | |
| 3-Nitro-Cinnamic Acid SCHEMBL7990708 | 0.95 | MAPT (0.69) | MAPTMAOBNFE2L2ALDH1A1MEN1 | |
| SCHEMBL5209312 | 0.89 | MAPT (0.62) | MAPTMAOBNFE2L2ALDH1A1MEN1 | |
| SCHEMBL5209309 | 0.89 | MAPT (0.62) | MAPTMAOBNFE2L2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |