Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 7/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203831 | 0.77 | TSHR (0.46) | L3MBTL1APLNRTDP1SMN1; SMN2LMNA | |
| SCHEMBL11508032 | 0.69 | L3MBTL1 (0.45) | L3MBTL1APLNRTDP1SMN1; SMN2LMNA | |
| SCHEMBL24759505 | 0.68 | POLB (0.50) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL11293066 | 0.68 | IDH1 (0.34) | ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL11506676 | 0.65 | ALDH1A1 (0.41) | L3MBTL1APLNRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30067927 | 0.64 | L3MBTL1 (0.44) | L3MBTL1APLNRTDP1SMN1; SMN2LMNA | |
| SCHEMBL5203856 | 0.64 | ALDH1A1 (0.33) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL5207275 | 0.64 | POLB (0.35) | L3MBTL1ALDH1A1KMT2AMEN1NR1I2 | |
| SCHEMBL24644594 | 0.64 | ALDH1A1 (0.41) | TDP1ALDH1A1SMN1; SMN2LMNACASR | |
| SCHEMBL11507037 | 0.63 | ALDH1A1 (0.47) | L3MBTL1APLNRTDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802590-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | Pharmacia & Upjohn Company LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040666-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-04-20 | — | — | WO | disclosed |
| US-4152426-A | NEMATOCIDES, MITICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-01 | — | — | US | disclosed |