Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 4/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MGAM | O43451 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207716 | 0.92 | MEN1 (0.37) | RXFP1FLT3CXCR2MAPTALDH1A1 | |
| SCHEMBL5203984 | 0.80 | ALDH1A1 (0.41) | RXFP1FLT3MAPTCNR2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5207834 | 0.79 | PDE4D (0.41) | PDE4DMAPTCNR2ALDH1A1GAA | |
| Trifluoroacetic Acid SCHEMBL5280152 | 0.79 | ALDH1A1 (0.40) | RXFP1FLT3MAPTCNR2ALDH1A1 | |
| SCHEMBL5214004 | 0.79 | HDAC1 (0.45) | GLS | |
| Trifluoroacetic Acid SCHEMBL5628234 | 0.78 | ALDH1A1 (0.38) | RXFP1FLT3MAPTCNR2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5207793 | 0.77 | PDE4D (0.40) | PDE4DMAPTCNR2ALDH1A1GAA | |
| Trifluoroacetic Acid SCHEMBL5207372 | 0.77 | RORC (0.47) | FLT3MAPTKMT2ANPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5209718 | 0.75 | FLT3 (0.39) | RXFP1FLT3MAPTALDH1A1GAA | |
| Trifluoroacetic Acid SCHEMBL5204002 | 0.75 | FLT3 (0.38) | RXFP1FLT3MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |