Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211150 | 0.91 | HRH3 (0.61) | ALDH1A1HRH3KDM4EPOLBHPGD | |
| SCHEMBL5210399 | 0.85 | HRH3 (0.62) | ALDH1A1HRH3KDM4EPOLBHPGD | |
| SCHEMBL5209593 | 0.84 | ALDH1A1 (0.64) | ALDH1A1HRH3KDM4EPOLBHPGD | |
| Hydrochloric Acid SCHEMBL5210915 | 0.83 | HRH3 (0.73) | HRH3 | |
| SCHEMBL5210748 | 0.81 | HRH3 (0.76) | HRH3 | |
| SCHEMBL5212236 | 0.81 | HRH3 (0.76) | HRH3 | |
| SCHEMBL5208889 | 0.80 | HRH3 (0.56) | HRH3 | |
| SCHEMBL5213801 | 0.80 | HRH3 (0.56) | HRH3 | |
| SCHEMBL5210281 | 0.79 | HRH3 (0.77) | HRH3 | |
| SCHEMBL1744040 | 0.79 | ALDH1A1 (0.62) | ALDH1A1HRH3KDM4EPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | claimed |