Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.56 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210990 | 0.92 | HRH3 (0.60) | ALDH1A1ADRA1AKDM4EPOLBHPGD | |
| SCHEMBL5208300 | 0.85 | L3MBTL3 (0.62) | ALDH1A1KDM4EHPGDHRH3L3MBTL3 | |
| SCHEMBL4134873 | 0.84 | ALDH1A1 (0.65) | ALDH1A1ADRA1AKDM4EPOLBHPGD | |
| Hydrochloric Acid SCHEMBL5213432 | 0.84 | L3MBTL3 (0.60) | ALDH1A1KDM4EHPGDHRH3L3MBTL3 | |
| SCHEMBL5209401 | 0.84 | ALDH1A1 (0.64) | ALDH1A1ADRA1AKDM4EPOLBHPGD | |
| SCHEMBL3095052 | 0.83 | HRH3 (0.67) | ALDH1A1ADRA1AKDM4EPOLBHPGD | |
| Hydrochloric Acid SCHEMBL5209555 | 0.83 | HRH3 (0.60) | ADRA1AHRH3 | |
| SCHEMBL5209685 | 0.83 | HRH3 (0.75) | ADRA1AHRH3 | |
| SCHEMBL5213411 | 0.80 | HRH3 (0.60) | ADRA1AHRH3 | |
| SCHEMBL5211791 | 0.80 | HRH3 (0.59) | ADRA1AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | claimed |