Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3032322 | 0.87 | ALDH1A1 (0.53) | ALDH1A1HTTKMT2ANPSR1MLYCD | |
| SCHEMBL994810 | 0.87 | HTT (0.54) | ALDH1A1HTTNPSR1MLYCDMAPT | |
| SCHEMBL3032698 | 0.85 | ALDH1A1 (0.54) | ALDH1A1HTTMLYCDMAPTLMNA | |
| SCHEMBL3033421 | 0.85 | HTT (0.58) | ALDH1A1HTTKMT2ANPSR1MLYCD | |
| SCHEMBL3038647 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HTTKMT2AKDM4EMAPT | |
| SCHEMBL1374393 | 0.84 | ALDH1A1 (0.53) | ALDH1A1HTTNPSR1MAPTLMNA | |
| SCHEMBL4899229 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HTTKMT2ANPSR1MLYCD | |
| SCHEMBL5211761 | 0.81 | LMNA (0.47) | ALDH1A1HTTKMT2ANPSR1KDM4E | |
| SCHEMBL3037380 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HTTKMT2ANPSR1MLYCD | |
| SCHEMBL3036700 | 0.80 | HTT (0.56) | ALDH1A1HTTNPSR1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156048-B1 | Heteroaroyl-isoxazoles and their use as herbicides | BAYER AGRICULTURE LTD (GB) | 2007-08-08 | — | — | EP | claimed |
| EP-1156048-B1 | Heteroaroyl-isoxazoles and their use as herbicides | BAYER AGRICULTURE LTD (GB) | 2007-08-08 | — | — | EP | disclosed |
| EP-0588357-B1 | Isoxazoles derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-06-12 | — | — | EP | disclosed |
| EP-1156048-A1 | Heteroaroyl-isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 2001-11-21 | — | — | EP | disclosed |
| EP-0588357-A1 | Isoxazoles derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-03-23 | — | — | EP | disclosed |