Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207297 | 0.88 | FAAH (0.36) | — | |
| SCHEMBL9199017 | 0.75 | GABRA1 (0.31) | — | |
| SCHEMBL206741 | 0.74 | CHRNB2 (0.30) | — | |
| SCHEMBL458794 | 0.74 | — | — | |
| SCHEMBL1069057 | 0.74 | TLR8 (0.33) | — | |
| SCHEMBL613044 | 0.74 | TLR8 (0.33) | — | |
| SCHEMBL9545554 | 0.73 | CHRNB2 (0.31) | GAAMAPT | |
| SCHEMBL8735132 | 0.72 | HTT (0.33) | ALDH1A1 | |
| SCHEMBL14941370 | 0.72 | NPC1 (0.35) | GAA | |
| SCHEMBL8590827 | 0.70 | CYP1A2 (0.35) | KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980867-B1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2007-08-08 | — | — | EP | disclosed |
| CN-1114602-C | Ketone derivatives and medicinal use thereof | TORAY INDUSTRIES (JP) | 2003-07-16 | — | — | CN | disclosed |
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |
| CN-1242771-A | Ketone derivatives and medicinal use thereof | TORAY INDUSTRIES (JP) | 2000-01-26 | — | — | CN | disclosed |