Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5245608 | 0.88 | OPRM1 (0.36) | OPRD1OPRM1OPRK1F2TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5211441 | 0.87 | RIPK1 (0.38) | OPRD1OPRM1OPRK1F2TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5210720 | 0.87 | HSD17B3 (0.38) | TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5629383 | 0.87 | POLB (0.36) | OPRD1OPRM1OPRK1F2TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5214432 | 0.86 | ACHE (0.42) | OPRD1OPRM1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL5211445 | 0.86 | POLB (0.44) | OPRD1OPRM1F2TPSAB1F10 | |
| Trifluoroacetic Acid SCHEMBL5215547 | 0.86 | RIPK1 (0.36) | OPRD1OPRM1OPRK1F2TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5208180 | 0.85 | RIPK1 (0.42) | F2F10 | |
| Trifluoroacetic Acid SCHEMBL5212450 | 0.85 | RIPK1 (0.39) | OPRD1OPRM1OPRK1F2TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5629844 | 0.85 | OPRM1 (0.34) | OPRD1OPRM1OPRK1F2TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240154-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |