Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RXRA | P19793 | 3/20 | 0.50 |
| ▸ | RXRB | P28702 | 3/20 | 0.50 |
| ▸ | RXRG | P48443 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359068 | 0.86 | CYP1A2 (0.76) | HTTCYP1A2PTGDR2ALDH1A1KDM4E | |
| Carbamic Acid SCHEMBL10358650 | 0.85 | HTT (0.64) | HTTCYP1A2PTGDR2ALDH1A1KDM4E | |
| SCHEMBL1362464 | 0.84 | HTT (0.64) | HTTCYP1A2PTGDR2ALDH1A1KDM4E | |
| SCHEMBL10358535 | 0.82 | HTT (0.73) | HTTCYP1A2PTGDR2ALDH1A1KDM4E | |
| SCHEMBL5215600 | 0.82 | HTT (0.64) | HTTCYP1A2PTGDR2ALDH1A1KDM4E | |
| SCHEMBL5210404 | 0.81 | PTGDR2 (0.76) | CYP1A2PTGDR2ALDH1A1RXRARXRB | |
| SCHEMBL10358652 | 0.80 | HTT (0.61) | HTTCYP1A2PTGDR2ALDH1A1KDM4E | |
| SCHEMBL1361085 | 0.79 | HTT (0.68) | HTTCYP1A2PTGDR2ALDH1A1KDM4E | |
| SCHEMBL10358692 | 0.79 | HTT (0.56) | HTTCYP1A2PTGDR2ALDH1A1KDM4E | |
| SCHEMBL1361173 | 0.78 | HTT (0.62) | HTTCYP1A2PTGDR2ALDH1A1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183276-B2 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20050090534-A1 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1486490-A1 | AZOLE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-3933838-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANALGESICS, ANTIBACTERIAL, DEPRESSANTS, ANTIULCER, ANTICOUGH | INSTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090534-A1 | Azole compounds | AHR, NR0B2, NR2C2 | HTT 1097/4885CYP1A2 98/4885PTGDR2 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.