Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1361173 | 0.93 | HTT (0.62) | HTTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL10669061 | 0.88 | HTT (0.60) | HTTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL1362464 | 0.88 | HTT (0.64) | HTTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL5209901 | 0.82 | HTT (0.66) | HTTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL5395517 | 0.80 | HSD17B10 (0.46) | HTTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL10358652 | 0.79 | HTT (0.61) | HTTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL11161509 | 0.78 | ALDH1A1 (0.76) | HTTALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10358535 | 0.76 | HTT (0.73) | HTTALDH1A1GAASMN1; SMN2KDM4E | |
| Carbamic Acid SCHEMBL10358650 | 0.76 | HTT (0.64) | HTTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL27995931 | 0.76 | HTT (0.77) | HTTALDH1A1GAASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183276-B2 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20050090534-A1 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1486490-A1 | AZOLE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-3933838-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANALGESICS, ANTIBACTERIAL, DEPRESSANTS, ANTIULCER, ANTICOUGH | INSTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090534-A1 | Azole compounds | AHR, NR0B2, NR2C2 | HTT 1097/4885ALDH1A1 1651/4885GAA 4803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.