Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209943 | 0.94 | ENPP2 (0.47) | ENPP2LMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL5212575 | 0.94 | ENPP2 (0.49) | ENPP2IDO1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5212780 | 0.91 | IDO1 (0.42) | ENPP2IDO1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5206933 | 0.91 | ENPP2 (0.47) | ENPP2IDO1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5212903 | 0.90 | ENPP2 (0.46) | ENPP2IDO1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5210727 | 0.90 | TRPV1 (0.42) | ENPP2IDO1LMNASMN1; SMN2KMT2A | |
| SCHEMBL5209936 | 0.88 | LMNA (0.50) | ENPP2LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL5214872 | 0.88 | ENPP2 (0.41) | ENPP2IDO1LMNASMN1; SMN2KMT2A | |
| SCHEMBL5206683 | 0.88 | ENPP2 (0.40) | ENPP2IDO1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5207799 | 0.88 | ENPP2 (0.45) | ENPP2LMNASMN1; SMN2L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183276-B2 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20050090534-A1 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1486490-A1 | AZOLE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2004-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090534-A1 | Azole compounds | AHR, NR0B2, NR2C2 | ENPP2 2808/4885IDO1 542/4885LMNA 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.