Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.57 |
| ▸ | OGA | O60502 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210466 | 0.84 | HRH3 (0.59) | HRH3OGAHSD11B1ACACB | |
| SCHEMBL5211731 | 0.83 | HRH3 (0.58) | HRH3HSD11B1ACACB | |
| SCHEMBL5210629 | 0.83 | HRH3 (0.57) | HRH3OGAHSD11B1 | |
| SCHEMBL5213801 | 0.81 | HRH3 (0.56) | HRH3ACACB | |
| SCHEMBL5212236 | 0.78 | HRH3 (0.76) | HRH3 | |
| SCHEMBL5210077 | 0.78 | HRH3 (0.58) | HRH3 | |
| SCHEMBL5213401 | 0.75 | HRH3 (0.53) | HRH3 | |
| SCHEMBL12469603 | 0.74 | HRH3 (0.46) | HRH3OGAHSD11B1ACACB | |
| SCHEMBL14844039 | 0.72 | HRH3 (1.00) | HRH3 | |
| SCHEMBL15347399 | 0.71 | HSD11B1 (0.44) | HRH3OGAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | claimed |