Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.49 |
| ▸ | PPARG | P37231 | 10/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210445 | 0.95 | PPARA (0.48) | PPARAPPARGFFAR1CYP2C9KCNH2 | |
| SCHEMBL5211867 | 0.93 | PPARG (0.48) | PPARAPPARGFFAR1CYP2C9KCNH2 | |
| SCHEMBL2520054 | 0.89 | PPARG (0.52) | PPARAPPARGFFAR1CYP2C9KCNH2 | |
| SCHEMBL2520051 | 0.89 | PPARG (0.52) | PPARAPPARGFFAR1CYP2C9KCNH2 | |
| SCHEMBL5209719 | 0.88 | PPARG (0.47) | PPARAPPARGFFAR1CYP2C9KCNH2 | |
| SCHEMBL5210569 | 0.88 | FFAR1 (0.53) | PPARAPPARGFFAR1MAPTTP53 | |
| SCHEMBL5210493 | 0.87 | PPARA (0.50) | PPARAPPARGFFAR1MAPTTP53 | |
| SCHEMBL2514695 | 0.87 | PPARG (0.51) | PPARAPPARGFFAR1CYP2C9KCNH2 | |
| SCHEMBL2514696 | 0.87 | PPARG (0.51) | PPARAPPARGFFAR1CYP2C9KCNH2 | |
| SCHEMBL5206326 | 0.84 | PPARA (0.44) | PPARAPPARGFFAR1CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448523-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | NOVARTIS AG (CH) | 2007-08-22 | — | — | EP | claimed |