Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 3/20 | 0.62 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.62 |
| ▸ | SMO | Q99835 | 2/20 | 0.57 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CTRC | Q99895 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28474694 | 1.00 | ENPP3 (0.62) | ENPP3ENPP1SMOHSD17B1HSD17B2 | |
| SCHEMBL11566150 | 0.91 | ENPP3 (0.72) | ENPP3ENPP1SMOHSD17B1HSD17B2 | |
| SCHEMBL3271684 | 0.91 | ENPP3 (0.72) | ENPP3ENPP1SMOHSD17B1HSD17B2 | |
| SCHEMBL5664564 | 0.89 | ENPP3 (0.75) | ENPP3ENPP1SMOHSD17B1HSD17B2 | |
| SCHEMBL278182 | 0.89 | ENPP3 (0.69) | ENPP3ENPP1SMOHSD17B1HSD17B2 | |
| Benzene SCHEMBL16781371 | 0.89 | ENPP3 (0.69) | ENPP3ENPP1SMOHSD17B1HSD17B2 | |
| SCHEMBL31606598 | 0.87 | ENPP3 (0.67) | ENPP3ENPP1SMOHSD17B1HSD17B2 | |
| SCHEMBL28478085 | 0.84 | HDAC1 (0.49) | ENPP3ENPP1SMOHSD17B1HSD17B2 | |
| SCHEMBL2095342 | 0.84 | HSD17B1 (0.62) | ENPP3ENPP1SMOHSD17B1HSD17B2 | |
| SCHEMBL7221671 | 0.82 | NPC1 (0.54) | ENPP3ENPP1SMOHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925338-A | Microwave preparation method of 2, 4-disubstituted oxazole compound | 浙江工业大学 | 2020-11-13 | — | — | CN | disclosed |
| US-7183276-B2 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20050090534-A1 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090534-A1 | Azole compounds | AHR, NR0B2, NR2C2 | ENPP3 4505/4885ENPP1 4628/4885SMO 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.