Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203929 | 0.84 | MAPK10 (0.41) | MEN1NPC1KMT2AALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL5204634 | 0.80 | MAPK10 (0.36) | MEN1NPC1KMT2AALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL5209718 | 0.80 | FLT3 (0.39) | MEN1NPC1KMT2AALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL5211954 | 0.79 | FLT3 (0.37) | MEN1NPC1KMT2AALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL5217152 | 0.79 | ALDH1A1 (0.37) | MEN1NPC1KMT2AALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL5208796 | 0.78 | SMN1; SMN2 (0.35) | MEN1NPC1KMT2AALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL5628234 | 0.77 | ALDH1A1 (0.38) | MEN1NPC1KMT2AALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL5214692 | 0.77 | MAOA (0.35) | OPRM1OPRD1ALDH1A1F2F10 | |
| Trifluoroacetic Acid SCHEMBL5214259 | 0.77 | MAOA (0.35) | OPRM1OPRD1F2F10 | |
| Trifluoroacetic Acid SCHEMBL5208332 | 0.77 | FLT3 (0.35) | MEN1NPC1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |