Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5211197 | 0.90 | FLT3 (0.36) | HPGDRAB9AKDM4ENPC1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4812316 | 0.88 | ALDH1A1 (0.33) | SMN1; SMN2HPGDRAB9AKDM4ENPC1 | |
| Trifluoroacetic Acid SCHEMBL5208294 | 0.88 | MEN1 (0.31) | POLBMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5209196 | 0.87 | IKBKB (0.33) | HTTTSHRGAA | |
| Trifluoroacetic Acid SCHEMBL5204674 | 0.87 | ENPP2 (0.34) | SMN1; SMN2HPGDRAB9AKDM4ENPC1 | |
| Trifluoroacetic Acid SCHEMBL5209741 | 0.86 | PDE4D (0.38) | HPGDKDM4EALDH1A1ADORA3MAPT | |
| Trifluoroacetic Acid SCHEMBL5204634 | 0.85 | MAPK10 (0.36) | SMN1; SMN2HPGDRAB9AKDM4ENPC1 | |
| SCHEMBL5203929 | 0.83 | MAPK10 (0.41) | SMN1; SMN2HPGDRAB9AKDM4ENPC1 | |
| Trifluoroacetic Acid SCHEMBL5208291 | 0.83 | MAPT (0.33) | SMN1; SMN2RAB9ANPC1MAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL5206929 | 0.78 | NPSR1 (0.34) | RAB9AKDM4ENPC1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |