Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209685 | 0.88 | HRH3 (0.75) | HRH3ADRA1A | |
| Hydrochloric Acid SCHEMBL5209555 | 0.85 | HRH3 (0.60) | HRH3ADRA1A | |
| SCHEMBL5213411 | 0.85 | HRH3 (0.60) | HRH3ADRA1APARP1 | |
| SCHEMBL5212236 | 0.83 | HRH3 (0.76) | HRH3 | |
| SCHEMBL5210990 | 0.83 | HRH3 (0.60) | HRH3ADRA1A | |
| SCHEMBL5212512 | 0.83 | HRH3 (0.61) | HRH3ADRA1A | |
| SCHEMBL5209775 | 0.83 | HRH3 (0.53) | HRH3 | |
| SCHEMBL5209593 | 0.80 | ALDH1A1 (0.64) | HRH3ADRA1A | |
| SCHEMBL1743034 | 0.80 | HRH3 (0.51) | HRH3PARP1 | |
| SCHEMBL5210629 | 0.78 | HRH3 (0.57) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | claimed |