Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10014259 | 0.91 | SMN1; SMN2 (0.50) | GAAPOLBSMN1; SMN2CTBP2ALDH1A1 | |
| SCHEMBL6469067 | 0.91 | SMN1; SMN2 (0.50) | GAAPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27479664 | 0.89 | POLB (0.42) | GAAPOLBSMN1; SMN2CTBP2ALDH1A1 | |
| SCHEMBL3953274 | 0.88 | NMT2 (0.46) | POLBSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1475977 | 0.86 | NMT2 (0.46) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10789386 | 0.86 | HPGD (0.52) | GAAPOLBSMN1; SMN2ALDH1A1APEX1 | |
| SCHEMBL10789393 | 0.86 | HPGD (0.52) | GAAPOLBSMN1; SMN2ALDH1A1APEX1 | |
| SCHEMBL14042690 | 0.82 | CA2 (0.54) | CTBP2LMNATDP1MEN1KMT2A | |
| SCHEMBL12834066 | 0.80 | HPGD (0.50) | POLBCTBP2ALDH1A1TDP1MEN1 | |
| SCHEMBL2044549 | 0.80 | LMNA (0.58) | GAAPOLBCTBP2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131302-B1 | IMIDAZOLIUM SALTS, INTERMEDIATES THERETO AND THEIR USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-01-29 | — | — | EP | disclosed |
| US-4689341-A | Antiarrhythmic imidazoles | SCHERING A.G. (DE) | 1987-08-25 | — | — | US | disclosed |
| US-4613609-A | Antiarrhythmic imidazoliums | SCHERING A. G. (DE) | 1986-09-23 | — | — | US | disclosed |
| US-4581370-A | Antiarrhythmic imidazoliums | SCHERING A.G. (DE) | 1986-04-08 | — | — | US | disclosed |
| EP-0131302-A2 | Imidazolium salts, intermediates thereto and their use | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-01-16 | — | — | EP | disclosed |