Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143040 | 1.00 | PTPN1 (0.68) | PTPN1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL5212814 | 0.87 | MAPK1 (0.71) | PTPN1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL2059537 | 0.87 | KDM4E (0.71) | PTPN1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL5338823 | 0.85 | KDM4E (0.56) | PTPN1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL11249189 | 0.83 | PTPN1 (0.57) | PTPN1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL7565582 | 0.82 | PTPN1 (0.51) | PTPN1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL742810 | 0.82 | ACHE (0.62) | PTPN1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL31229899 | 0.82 | ACHE (0.62) | PTPN1KDM4EHSD17B10ALDH1A1HPGD | |
| Acetic Acid SCHEMBL28743775 | 0.82 | KDM4E (0.70) | PTPN1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL18066345 | 0.81 | PTPN1 (1.00) | PTPN1KDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308615-A1 | SPHERICAL CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | W. R. Grace & Co.-Conn (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117355546-A | Spherical catalyst component for olefin polymerization | 格雷斯公司 | 2024-01-05 | — | — | CN | disclosed |
| WO-2022197491-A1 | SPHERICAL CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | W.R. GRACE & CO.-CONN. (US) | 2022-09-22 | — | — | WO | disclosed |