SCHEMBL3071643

SCHEMBL3071643

CC(C)SC(=O)SC(C)C

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.40
NOS1 P29475 1/20 0.40
NOS2 P35228 1/20 0.40
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14156174 0.85 NOS3 (0.32) NOS3NOS1NOS2
SCHEMBL23633747 0.85 NOS3 (0.38) NOS3NOS1NOS2
SCHEMBL10922978 0.83
SCHEMBL5212996 0.74
SCHEMBL2827696 0.74
SCHEMBL6964305 0.74
SCHEMBL13987916 0.72
SCHEMBL53676 0.72 TP53 (0.30) TP53
SCHEMBL20998266 0.72 SLC7A5 (0.36) NOS3NOS1NOS2TP53
SCHEMBL21234244 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11771715-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-10-03 US disclosed
US-11766449-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-09-26 US disclosed
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. 2023-07-20 US disclosed
US-11680192-B2 Functionalized (co)polymers for adhesive systems TESA SE (DE) 2023-06-20 US disclosed
US-11679120-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-06-20 US disclosed
CN-110167939-A Pyrrolo- [2,3-c] pyridine derivatives, preparation method and its application in medicine 江苏豪森药业集团有限公司 2019-08-23 CN disclosed
US-9765022-B2 Disulfide compounds for delivery of pharmaceutical agents TUFTS UNIVERSITY (US) 2017-09-19 US disclosed
US-20160082126-A1 NANOCOMPLEXES FOR DELIVERY OF SAPORIN UNIV TUFTS (US) 2016-03-24 US disclosed
US-20160009643-A1 DISULFIDE COMPOUNDS FOR DELIVERY OF PHARMACEUTICAL AGENTS TRUSTEES OF TUFTS COLLEGE 2016-01-14 US disclosed
US-8796389-B2 Method for reversible covalent crosslinking of adhesives TESA SE (DE) 2014-08-05 US disclosed
US-7235142-B2 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON (US) 2007-06-26 US disclosed
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
US-20040104377-A1 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON 2004-06-03 US disclosed
US-20040020568-A1 Non-toxic corrosion-protection conversion coats based on rare earth elements DAYTON, UNIVERSITY OF 2004-02-05 US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11771715-B2 Circular RNA compositions and methods RTCB, HNRNPA1, HNRNPAB NOS3 3957/4885NOS1 4099/4885NOS2 3569/4885
US-20160009643-A1 DISULFIDE COMPOUNDS FOR DELIVERY OF PHARMACEUTICAL AGENTS P4HB, PDIA6, PDIA5 NOS3 989/4885NOS1 683/4885NOS2 590/4885
US-20160082126-A1 NANOCOMPLEXES FOR DELIVERY OF SAPORIN SARNP, SAP30BP, SCP2 NOS3 3768/4885NOS1 3523/4885NOS2 3375/4885
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS RTCB, HNRNPA1, HNRNPAB NOS3 3957/4885NOS1 4099/4885NOS2 3569/4885
US-11679120-B2 Circular RNA compositions and methods RTCB, HNRNPA1, HNRNPAB NOS3 3957/4885NOS1 4099/4885NOS2 3569/4885
US-11766449-B2 Circular RNA compositions and methods RTCB, RNGTT, HNRNPAB NOS3 3953/4885NOS1 4152/4885NOS2 3614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.