Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216402 | 0.71 | SCD (0.47) | SCDTRPV1KMT2AALDH1A1MEN1 | |
| SCHEMBL5215981 | 0.71 | SCD (0.37) | SCDTRPV1ALDH1A1RXFP1RIPK1 | |
| SCHEMBL5213218 | 0.70 | SCD (0.46) | SCDMAOBPOLBALDH1A1RXFP1 | |
| SCHEMBL1476247 | 0.69 | MCHR1 (0.37) | POLBANO1KMT2AALDH1A1MEN1 | |
| SCHEMBL1475357 | 0.68 | GPR119 (0.54) | POLBKMT2AALDH1A1MEN1OPRD1 | |
| SCHEMBL12748498 | 0.67 | SLC6A2 (0.41) | POLBANO1KMT2AALDH1A1LMNA | |
| SCHEMBL1476787 | 0.67 | SIGMAR1 (0.45) | KMT2AALDH1A1LMNARXFP1SIGMAR1 | |
| SCHEMBL5213158 | 0.67 | SCD (0.45) | SCDKMT2AALDH1A1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL1475138 | 0.66 | SLC6A2 (0.40) | POLBANO1KMT2AALDH1A1LMNA | |
| SCHEMBL5213284 | 0.66 | SCD (0.51) | SCDPOLBKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484327-B1 | NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINE THEREOF | EISAI R&D MAN CO LTD (JP) | 2007-08-01 | — | — | EP | disclosed |