SCHEMBL5213655

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28547976	0.83	ACP3 (0.40)	APPKDM4EMAPTTDP1ACP3
	SCHEMBL30840274	0.83	APP (0.47)	APPPTGS1PTGS2KDM4EMAPT
	SCHEMBL5796124	0.83	APP (0.47)	APPPTGS1PTGS2KDM4EMAPT
	SCHEMBL27278587	0.83	APP (0.56)	APPPTGS1PTGS2ACP3LMNA
	SCHEMBL27280857	0.83	APP (0.47)	APPPTGS1PTGS2KDM4EMAPT
	SCHEMBL27276632	0.83	APP (0.47)	APPPTGS1PTGS2
	SCHEMBL30841003	0.83	APP (0.47)	APPPTGS1PTGS2
	SCHEMBL1653533	0.81	PTGS1 (0.62)	PTGS1PTGS2ACP3PSEN1PSEN2
	SCHEMBL29484096	0.81	PTGS1 (0.62)	PTGS1PTGS2ACP3PSEN1PSEN2
	SCHEMBL1492817	0.81	PTGS1 (0.62)	PTGS1PTGS2ACP3PSEN1PSEN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.