Gemopatrilat

Gemopatrilat

SCHEMBL5213866

CC1(C)CCC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C(=O)N1CC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACE P12821 6/20 1.00
MME P08473 5/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gemopatrilat SCHEMBL1973289 1.00 ACE (1.00) ACEMME
Gemopatrilat SCHEMBL13575789 1.00 ACE (1.00) ACEMME
SCHEMBL12768553 0.91 ACE (0.83) ACEMME
SCHEMBL8837701 0.89 ACE (0.80) ACEMME
SCHEMBL8428348 0.89 ACE (0.80) ACEMME
SCHEMBL8432189 0.89 ACE (0.80) ACEMME
SCHEMBL8837724 0.89 ACE (0.80) ACEMME
SCHEMBL7540477 0.85 ACE (0.73) ACEMME
SCHEMBL7540483 0.85 ACE (0.73) ACEMME
SCHEMBL7664525 0.82 ACE (0.69) ACEMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739293-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF AUTOIMMUNE DISORDERS AZURA OPHTHALMICS LTD (IL) 2026-05-13 EP claimed
EP-4739291-A2 ADMINISTRATION OF KERATOLYTICS TO OCULAR AND PERIOCULAR SURFACES AZURA OPHTHALMICS LTD (IL) 2026-05-13 EP claimed
WO-2026041906-A1 SEMI-SOLID PHARMACEUTICAL COMPOSITION MICRO-DISPENSER Azura Ophthalmics Ltd. (IL) 2026-02-26 WO claimed
US-20250082608-A1 TREATMENT AND PREVENTION OF GLOMERULAR DISEASE SINGAPORE HEALTH SERVICES PTE LTD. (SG) 2025-03-13 US claimed
WO-2025012700-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF AUTOIMMUNE DISORDERS Azura Ophthalmics Ltd. (IL) 2025-01-16 WO claimed
WO-2025012701-A2 ADMINISTRATION OF KERATOLYTICS TO OCULAR AND PERIOCULAR SURFACES Azura Ophthalmics Ltd. (IL) 2025-01-16 WO claimed
EP-4448096-A1 TREATMENT AND PREVENTION OF GLOMERULAR DISEASE Singapore Health Services Pte. Ltd. (SG) 2024-10-23 EP claimed
WO-2024100454-A2 COMPOSITION AND METHODS FOR IMPROVING SIGNS AND SYMPTOMS OF OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2024-05-16 WO claimed
WO-2023111196-A1 TREATMENT AND PREVENTION OF GLOMERULAR DISEASE SINGAPORE HEALTH SERVICES PTE. LTD. (SG) 2023-06-22 WO claimed
WO-2022265697-A1 COMPOSITIONS FOR TREATING VIRAL INFECTIONS AND METHODS FOR SAME Tiger Development, LLC (US) 2022-12-22 WO claimed
US-6486315-B2 RECRYSTALLIZING MERCAPTOALKANOYLAMINO LACTAM ACID UNDER BASIC CONDITIONS USING AN AGENT THAT MINIMIZES AMOUNT OF DISULFIDES BRISTOL-MYERS SQUIBB CO. 2002-11-26 US claimed
US-6444810-B1 ACYLMERCAPTOALKANOYLAMINO LACTAM ESTERS OR ACIDS ARE CONVERTED TO THE CORRESPONDING MERCAPTOALKANOYLAMINO LACTAM ESTER OR ACID UNDER BASIC CONDITIONS USING AN AGENT THAT MINIMIZES AMOUNT OF DISULFIDES BRISTOL-MYERS SQUIBB CO. 2002-09-03 US claimed
EP-1051419-A4 DEPROTECTION AND RECRYSTALLIZATION PROCESSES BRISTOL MYERS SQUIBB CO (US) 2002-08-28 EP claimed
US-20020086995-A1 Recrystallization processes KRONENTHAL DAVID R (US) 2002-07-04 US claimed
US-20020086994-A1 Acylmercaptoalkanoylamino lactam esters or acids are converted to the corresponding mercaptoalkanoylamino lactam ester or acid under basic conditions using an agent that minimizes amount of disulfides KRONENTHAL DAVID R (US) 2002-07-04 US claimed
US-20020004500-A1 Vasopeptidase Inhibitors to treat isolated systolic hypertension BRISTOL-MYERS SQUIBB COMPANY 2002-01-10 US claimed
WO-2001074348-A2 VASOPEPTIDASE INHIBITORS TO TREAT ISOLATED SYSTOLIC HYPERTENSION BRISTOL-MYERS SQUIBB CO. (US) 2001-10-11 WO claimed
EP-1051419-A1 DEPROTECTION AND RECRYSTALLIZATION PROCESSES BRISTOL-MYERS SQUIBB COMPANY (US) 2000-11-15 EP claimed
US-6140319-A ADMINISTERING AN VASOPEPTIDASE INHIBITOR FOR TREATING AND/OR RELIEVING THE SYMPTOMS OF ANGINA PECTORIS BRISTOL-MYERS SQUIBB CO. (US) 2000-10-31 US claimed
WO-1999035145-A1 DEPROTECTION AND RECRYSTALLIZATION PROCESSES BRISTOL-MYERS SQUIBB COMPANY (US) 1999-07-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004500-A1 Vasopeptidase Inhibitors to treat isolated systolic hypertension PREP, VASP, ANPEP ACE 6/4885MME 21/4885
US-20020086994-A1 Acylmercaptoalkanoylamino lactam esters or acids are converted to the corresponding mercaptoalkanoylamino lactam ester or acid under basic conditions using an agent that minimizes amount of disulfides MPST, PTMS, TST ACE 315/4885MME 493/4885
US-20020086995-A1 Recrystallization processes MPST, TST, SLC39A11 ACE 1296/4885MME 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.