Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5213218 | 0.74 | SCD (0.46) | SCDHTR2CKDM4EALDH1A1NPC1 | |
| SCHEMBL27599446 | 0.69 | HTR2C (0.36) | L3MBTL1MAPTKMT2AHTR2CKDM4E | |
| SCHEMBL1475454 | 0.68 | DCPS (0.46) | SCDHTR2CCYP2D6 | |
| SCHEMBL5213811 | 0.68 | SCD (0.76) | SCDSSTR1SSTR4 | |
| SCHEMBL5522793 | 0.67 | L3MBTL1 (0.44) | L3MBTL1KMT2AKDM4EMEN1CYP1A2 | |
| SCHEMBL5214241 | 0.67 | SCD (0.45) | SCDKDM4EALDH1A1NPC1 | |
| SCHEMBL1476800 | 0.67 | HCAR2 (0.37) | L3MBTL1GAAMAPTHTTKMT2A | |
| SCHEMBL2563921 | 0.65 | SCD (0.73) | SCD | |
| SCHEMBL1475168 | 0.65 | SLC6A2 (0.47) | L3MBTL1KMT2AKDM4EMEN1CYP1A2 | |
| SCHEMBL30674532 | 0.65 | IDO1 (0.52) | L3MBTL1MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484327-B1 | NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINE THEREOF | EISAI R&D MAN CO LTD (JP) | 2007-08-01 | — | — | EP | disclosed |