Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5213218 | 0.84 | SCD (0.46) | SCDKDM4EHSD17B10ALDH1A1RXFP1 | |
| SCHEMBL5217243 | 0.71 | SCD (0.48) | SCDKDM4EALDH1A1RXFP1 | |
| SCHEMBL5213370 | 0.69 | SCD (0.41) | SCDALDH1A1RXFP1RIPK1MAOB | |
| SCHEMBL1475083 | 0.67 | MAOA (0.38) | KDM4EALDH1A1MAOBPOLBMAOA | |
| SCHEMBL5214232 | 0.67 | SCD (0.48) | SCDKDM4EALDH1A1NPC1 | |
| SCHEMBL5215166 | 0.67 | SCD (0.43) | SCD | |
| SCHEMBL5215986 | 0.66 | SCD (0.37) | SCDKDM4EALDH1A1RXFP1RIPK1 | |
| SCHEMBL5215981 | 0.66 | SCD (0.37) | SCDKDM4EALDH1A1RXFP1RIPK1 | |
| SCHEMBL5210901 | 0.65 | SCD (0.61) | SCDKDM4EALDH1A1SIGMAR1 | |
| SCHEMBL5213158 | 0.64 | SCD (0.45) | SCDKDM4EALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484327-B1 | NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINE THEREOF | EISAI R&D MAN CO LTD (JP) | 2007-08-01 | — | — | EP | disclosed |