Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932209 | 0.86 | MAOA (0.57) | MAOAMAOBNPC1RAB9A | |
| SCHEMBL4576841 | 0.84 | FDPS (0.57) | AKR1C3MAOAMAOBNPC1CYP2C9 | |
| SCHEMBL5214421 | 0.84 | MAOA (0.56) | AKR1C3PTGESALOX5PPARGMAOA | |
| SCHEMBL420250 | 0.83 | TTR (0.52) | AKR1C3ALOX5MAOAMAOBNPC1 | |
| SCHEMBL77752 | 0.82 | FDPS (0.50) | NPC1CYP2C9RAB9ANPSR1FDPS | |
| SCHEMBL2933672 | 0.81 | CYP2C9 (0.58) | AKR1C3PTGESALOX5PPARGNPC1 | |
| SCHEMBL1299319 | 0.80 | HPGD (0.61) | AKR1C3PPARGMAOAMAOBNPC1 | |
| SCHEMBL5215514 | 0.80 | ALDH1A1 (0.44) | AKR1C3PTGESALOX5PPARGMAOA | |
| SCHEMBL7255384 | 0.79 | AKR1C3 (0.48) | AKR1C3PTGESALOX5PPARGNPC1 | |
| SCHEMBL9077155 | 0.79 | TACR2 (0.54) | AKR1C3MAOAMAOBNPSR1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313471-B1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | UCB SA (BE) | 2007-04-11 | — | — | EP | disclosed |
| EP-1313471-B1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | UCB SA (BE) | 2007-04-11 | — | — | EP | disclosed |
| US-7105554-B2 | Benzylidene thiazolidinediones and their use as antimycotic agents | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 2006-09-12 | — | — | US | disclosed |
| US-20040006112-A1 | Benzylidene thiazolidinediones and their use as antimycotic agents | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-01-08 | — | — | US | disclosed |
| EP-1313471-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | Oxford GlycoSciences (UK) Limited (GB) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002017915-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006112-A1 | Benzylidene thiazolidinediones and their use as antimycotic agents | SLC5A2, OXSR1, SLC5A1 | AKR1C3 505/4885PTGES 4231/4885ALOX5 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.