SCHEMBL521500

SCHEMBL521500

C=C(CCCCOCCC)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 6/20 0.39
CES2 O00748 1/20 0.37
THRB P10828 2/20 0.36
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36
PGGT1B P53609 1/20 0.36
AKR1B1 P15121 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 3/20 0.35
TBXAS1 P24557 1/20 0.35
GPR84 Q9NQS5 2/20 0.34
PPARG P37231 2/20 0.34
PPARD Q03181 2/20 0.34
PPARA Q07869 2/20 0.34
SLC22A6 Q4U2R8 1/20 0.34
SLC22A8 Q8TCC7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL521492 0.98 EPHX2 (0.41) EPHX2CES2THRBFNTAFNTB
SCHEMBL303832 0.94 TSHR (0.35) EPHX2CES2THRBFNTAFNTB
SCHEMBL5166180 0.93 EPHX2 (0.40) EPHX2CES2THRBFNTAFNTB
SCHEMBL6273168 0.92 TSHR (0.43) EPHX2CES2THRBFNTAFNTB
SCHEMBL871679 0.91 CES2 (0.44) CES2THRBFNTAFNTBPGGT1B
SCHEMBL16196269 0.89 THRB (0.38) EPHX2CES2THRBALDH1A1TSHR
SCHEMBL5830403 0.89 CES2 (0.46) EPHX2CES2THRBFNTAFNTB
SCHEMBL5386601 0.87 CES2 (0.48) CES2THRBFNTAFNTBPGGT1B
SCHEMBL5399493 0.87 CES2 (0.48) CES2THRBFNTAFNTBPGGT1B
SCHEMBL5382939 0.87 CES2 (0.48) CES2THRBFNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4321602-A1 SULFUR FREE POLY ALKYL(METH)ACRYLATE COPOLYMERS AS VISCOSITY INDEX IMPROVERS IN LUBRICANTS Evonik Operations GmbH (DE) 2024-02-14 EP disclosed
US-11795413-B2 Viscosity index improver and lubricant compositions thereof EVONIK OPERATIONS GMBH (DE) 2023-10-24 US disclosed
EP-4060009-B1 VISCOSITY INDEX IMPROVER AND LUBRICANT COMPOSITIONS THEREOF EVONIK OPERATIONS GMBH (DE) 2023-05-03 EP disclosed
US-20220306962-A1 VISCOSITY INDEX IMPROVER AND LUBRICANT COMPOSITIONS THEREOF EVONIK OPERATIONS GMBH (DE) 2022-09-29 US disclosed
EP-3778839-B1 VISCOSITY INDEX IMPROVER WITH IMPROVED SHEAR-RESISTANCE EVONIK OPERATIONS GMBH (DE) 2021-08-04 EP disclosed
EP-3778839-A1 VISCOSITY INDEX IMPROVER WITH IMPROVED SHEAR-RESISTANCE Evonik Operations GmbH (DE) 2021-02-17 EP disclosed
US-9186441-B2 Surface treating agent, filtering material for filter, and blood treatment filter TERUMO KABUSHIKI KAISHA (JP) 2015-11-17 US disclosed
US-20120024779-A1 SURFACE TREATING AGENT, FILTERING MATERIAL FOR FILTER, AND BLOOD TREATMENT FILTER TERUMO KABUSHIKI KAISHA (JP) 2012-02-02 US disclosed
EP-1489410-A2 Copolymers for membranes in extended use planar sensors Novartis AG (CH) 2004-12-22 EP disclosed
US-3960762-A Production of absorbents BAYER AKTIENGESELLSCHAFT (DT) 1976-06-01 US disclosed