Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211421 | 0.97 | TNKS (0.42) | PIN1TNKSACHEBACE1POLB | |
| SCHEMBL5211058 | 0.94 | CNR1 (0.39) | PIN1CNR1TNKSACHEBACE1 | |
| SCHEMBL5208205 | 0.93 | TP53 (0.42) | TNKSPOLBMAPTCETP | |
| SCHEMBL5210100 | 0.93 | PTGDR2 (0.40) | PIN1TNKSACHEBACE1POLB | |
| SCHEMBL5207954 | 0.92 | RAB9A (0.42) | TNKSPOLBMAPT | |
| SCHEMBL5210803 | 0.91 | AURKA (0.43) | TNKSMAPTAURKACETP | |
| SCHEMBL5211745 | 0.91 | MAPT (0.41) | CNR1TNKSPOLBMAPT | |
| SCHEMBL5211475 | 0.91 | MAPT (0.41) | TNKSPOLBMAPT | |
| SCHEMBL5208761 | 0.91 | POLB (0.44) | CNR1TNKSPOLBMAPTCETP | |
| SCHEMBL5212587 | 0.91 | THRB (0.50) | MAPTAURKACETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183276-B2 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20050090534-A1 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1486490-A1 | AZOLE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2004-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090534-A1 | Azole compounds | AHR, NR0B2, NR2C2 | PIN1 507/4885CNR1 193/4885TNKS 4684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.