Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 3/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215997 | 0.85 | CCR5 (0.40) | CCR5ACHEHTR4 | |
| SCHEMBL2842638 | 0.85 | CCR5 (0.36) | CCR5FFAR2ACHEHTR4 | |
| SCHEMBL5245515 | 0.85 | CCR5 (0.40) | CCR5FFAR2MEN1KMT2A | |
| SCHEMBL5217130 | 0.82 | CCR5 (0.41) | CCR5FFAR2 | |
| SCHEMBL5217137 | 0.82 | CCR5 (0.41) | CCR5FFAR2 | |
| SCHEMBL4213338 | 0.80 | CCR5 (0.37) | CCR5HTR4KMT2A | |
| SCHEMBL5214392 | 0.80 | POLB (0.39) | CCR5ACHEHTR4MEN1KMT2A | |
| SCHEMBL5215178 | 0.79 | CCR5 (0.45) | CCR5FFAR2 | |
| SCHEMBL5214744 | 0.79 | SLC6A4 (0.35) | FFAR2 | |
| SCHEMBL13478936 | 0.74 | CCR5 (0.44) | CCR5ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228367-B1 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | ASUBIO PHARMA CO LTD (JP) | 2007-09-26 | — | — | EP | disclosed |
| EP-1228367-B1 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | ASUBIO PHARMA CO LTD (JP) | 2007-09-26 | — | — | EP | disclosed |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. | 2006-08-10 | — | — | US | disclosed |
| US-7067533-B2 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. (JP) | 2006-06-27 | — | — | US | disclosed |
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | SCN10A, CAMK2A, CAMK2B | CCR5 3787/4885FFAR2 2860/4885ACHE 1314/4885 |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | NR0B1, NR0B2, NR4A1 | CCR5 2502/4885FFAR2 782/4885ACHE 868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.