Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 6/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 9/20 | 0.38 |
| ▸ | DRD4 | P21917 | 7/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5217130 | 1.00 | CCR5 (0.41) | CCR5SLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL4217091 | 0.91 | DRD2 (0.40) | CCR5SLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL5217019 | 0.84 | POLB (0.43) | CCR5SLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL5217015 | 0.84 | POLB (0.43) | CCR5SLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL5215512 | 0.82 | CCR5 (0.37) | CCR5FFAR2 | |
| SCHEMBL5215178 | 0.80 | CCR5 (0.45) | CCR5DRD4FFAR2 | |
| SCHEMBL5215997 | 0.76 | CCR5 (0.40) | CCR5 | |
| SCHEMBL5245515 | 0.76 | CCR5 (0.40) | CCR5FFAR2 | |
| SCHEMBL4207381 | 0.74 | HPGD (0.45) | SLC6A2SLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL4368100 | 0.72 | OPRM1 (0.48) | CCR5SLC6A3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228367-B1 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | ASUBIO PHARMA CO LTD (JP) | 2007-09-26 | — | — | EP | disclosed |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. | 2006-08-10 | — | — | US | disclosed |
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | SCN10A, CAMK2A, CAMK2B | CCR5 3787/4885SLC6A2 1131/4885SLC6A4 605/4885 |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | NR0B1, NR0B2, NR4A1 | CCR5 2502/4885SLC6A2 658/4885SLC6A4 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.