Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024769 | 0.81 | NR3C2 (0.58) | TSHRALDH1A1SMN1; SMN2NR3C2HTT | |
| SCHEMBL31726567 | 0.75 | ALDH1A1 (0.50) | TSHRALDH1A1MAPTSMN1; SMN2EGFR | |
| SCHEMBL1268756 | 0.75 | ALDH1A1 (0.50) | TSHRALDH1A1MAPTSMN1; SMN2EGFR | |
| SCHEMBL693898 | 0.75 | CHKA (0.42) | ALDH1A1SMN1; SMN2NR3C2EGFRHTT | |
| Hydrochloric Acid SCHEMBL11291701 | 0.74 | ALDH1A1 (0.48) | TSHRALDH1A1MAPTSMN1; SMN2EGFR | |
| SCHEMBL9144890 | 0.71 | BRD4 (0.41) | TSHRMAPT | |
| SCHEMBL6757753 | 0.70 | POLB (0.46) | MTNR1AMTNR1BTSHRALDH1A1MAPT | |
| SCHEMBL24783814 | 0.69 | CYP2D6 (0.39) | TSHRALDH1A1MAPTSMN1; SMN2EGFR | |
| SCHEMBL29947757 | 0.69 | SIGMAR1 (0.47) | TSHRALDH1A1EGFRSRCKDM1A | |
| SCHEMBL21969636 | 0.68 | TSHR (0.52) | TSHRALDH1A1MAPTKDM1ANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633733-A4 | CANNABINOID DERIVATIVES, METHODS OF MAKING, AND USE THEREOF | UNIV TENNESSEE RES CORP (US) | 2007-02-28 | — | — | EP | disclosed |
| EP-1633733-A1 | CANNABINOID DERIVATIVES, METHODS OF MAKING, AND USE THEREOF | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004113320-A1 | CANNABINOID DERIVATIVES, METHODS OF MAKING, AND USE THEREOF | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2004-12-29 | — | — | WO | disclosed |