Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.56 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390734 | 0.95 | ALDH1A1 (0.67) | ALDH1A1GAAITGA4ITGB7OPRK1 | |
| SCHEMBL5215651 | 0.95 | ALDH1A1 (0.67) | ALDH1A1GAAITGA4ITGB7OPRK1 | |
| Hydrochloric Acid SCHEMBL7408488 | 0.88 | ITGA4 (0.71) | ALDH1A1GAAITGA4ITGB7OPRK1 | |
| Hydrochloric Acid SCHEMBL7454715 | 0.88 | ITGA4 (0.71) | ALDH1A1GAAITGA4ITGB7OPRK1 | |
| SCHEMBL3739594 | 0.88 | ATM (0.60) | ALDH1A1GAAATMFPR2THRB | |
| Hydrochloric Acid SCHEMBL7225746 | 0.86 | ATM (0.58) | ALDH1A1GAAATMFPR2THRB | |
| SCHEMBL6375429 | 0.80 | ITGA4 (0.73) | ALDH1A1GAAITGA4ITGB7ATM | |
| SCHEMBL6375427 | 0.80 | ITGA4 (0.73) | ALDH1A1GAAITGA4ITGB7ATM | |
| SCHEMBL28067051 | 0.80 | ATM (0.55) | ALDH1A1GAAATMTHRBCYP2C9 | |
| SCHEMBL22444688 | 0.79 | ALDH1A1 (0.56) | ALDH1A1GAAITGA4ITGB7CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276732-B1 | AMIDES OF R-2-(AMINOARYL)-PROPIONIC ACIDS FOR USE IN THEPREVENTION OF LEUCOCYTE ACTIVATION\ | DOMPE PHA R MA SPA RES & MFG (IT) | 2007-09-26 | — | — | EP | disclosed |