Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4474316 | 0.99 | KDM1A (0.43) | KDM1ACYP11B1CYP11B2C5AR1CHRM2 | |
| SCHEMBL4465415 | 0.81 | NPC1 (0.36) | CYP11B1CYP11B2 | |
| SCHEMBL4467650 | 0.81 | — | — | |
| SCHEMBL4463819 | 0.79 | HSD11B1 (0.38) | CYP11B1CYP11B2 | |
| SCHEMBL4473740 | 0.79 | KDM1A (0.46) | KDM1ACYP11B1CYP11B2C5AR1CHRM2 | |
| Bromide SCHEMBL4466117 | 0.78 | HSD11B1 (0.37) | CYP11B1CYP11B2 | |
| SCHEMBL4467652 | 0.78 | KDM1A (0.43) | KDM1ACYP11B1CYP11B2CHRM2CHRM4 | |
| SCHEMBL5219426 | 0.78 | HSD11B1 (0.32) | — | |
| SCHEMBL5217300 | 0.78 | HPGDS (0.37) | CYP11B1CYP11B2ALDH1A1HSD17B10 | |
| Bromide SCHEMBL4460345 | 0.77 | HSD11B1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465893-B1 | DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO (3.2.1) OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | EP | claimed |