SCHEMBL5215925

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8011429	0.79	RPS6KA3 (0.69)	RPS6KA3CDK2MELKEEF2KPLK4
	SCHEMBL6620051	0.77	PTGS2 (0.55)	PTGS2PTGS1RPS6KA3
	SCHEMBL7539198	0.76	PTGS2 (0.56)	PTGS2PTGS1
	SCHEMBL6620090	0.76	PTGS2 (0.56)	PTGS2PTGS1
	SCHEMBL388018	0.74	ENPP2 (0.86)	ENPP2PTGS2PTGS1MELKMAP4K4
	SCHEMBL8637748	0.72	PTGS2 (0.56)	PTGS2PTGS1
	SCHEMBL7779618	0.72	PTGS2 (0.57)	PTGS2PTGS1
	SCHEMBL6438782	0.72	PTGS2 (0.52)	PTGS2PTGS1
	SCHEMBL1535	0.72	ENPP2 (1.00)	ENPP2PTGS2PTGS1MELKMAP4K4
	SCHEMBL7777288	0.71	PTGS2 (0.45)	PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.