Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067283 | 0.87 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL8640822 | 0.85 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL8069284 | 0.82 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL6438544 | 0.82 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL8068397 | 0.80 | PTGS2 (0.53) | PTGS2 | |
| SCHEMBL8195776 | 0.80 | CA2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL8058037 | 0.79 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL8196010 | 0.78 | CA2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL8187580 | 0.78 | TP53 (0.37) | PTGS2PTGS1 | |
| SCHEMBL7779618 | 0.77 | PTGS2 (0.57) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856000-A1 | 1,3,5-TRISUBSTITUTED PYRAZOLES FOR TREAMENT OF INFLAMMATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997013755-A1 | 1,3,5-TRISUBSTITUTED PYRAZOLES FOR TREAMENT OF INFLAMMATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-17 | — | — | WO | disclosed |