Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | NAMPT | P43490 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11551985 | 0.85 | ALDH1A1 (0.80) | ALDH1A1NAMPTMAPTCYP11B1CYP11B2 | |
| SCHEMBL25277062 | 0.85 | ALDH1A1 (0.79) | ALDH1A1NAMPTMAPTCYP11B1CYP11B2 | |
| SCHEMBL5218284 | 0.84 | KCNK3 (0.58) | ALDH1A1NAMPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5215208 | 0.83 | RAB9A (0.60) | ALDH1A1NAMPTMAPTMEN1KMT2A | |
| SCHEMBL146250 | 0.80 | NAMPT (1.00) | NAMPTMAPTMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11844425 | 0.80 | NAMPT (1.00) | NAMPTMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29374071 | 0.80 | NAMPT (1.00) | NAMPTMAPTMEN1KMT2ASMN1; SMN2 | |
| Bromide SCHEMBL11621172 | 0.79 | NAMPT (0.98) | NAMPTMAPTMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11838523 | 0.79 | NAMPT (0.98) | NAMPTMAPTMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11847957 | 0.79 | NAMPT (0.98) | NAMPTMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198456-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2007-09-19 | — | — | EP | claimed |
| EP-1198456-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2007-09-19 | — | — | EP | disclosed |