Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.80 |
| ▸ | NAMPT | P43490 | 1/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25277062 | 0.89 | ALDH1A1 (0.79) | ALDH1A1NAMPTCYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL5215933 | 0.85 | ALDH1A1 (0.73) | ALDH1A1NAMPTCYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL8373850 | 0.82 | KMT2A (0.75) | ALDH1A1NAMPTCYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL10761136 | 0.82 | ROCK2 (0.77) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL28276093 | 0.82 | NPC1 (0.70) | ALDH1A1NAMPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28871814 | 0.82 | ALDH1A1 (0.75) | ALDH1A1CYP11B1CYP11B2SMN1; SMN2MEN1 | |
| SCHEMBL31006484 | 0.82 | ALDH1A1 (0.75) | ALDH1A1CYP11B1CYP11B2SMN1; SMN2MEN1 | |
| SCHEMBL11554887 | 0.78 | KMT2A (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL11558352 | 0.78 | RAB9A (0.71) | ALDH1A1SMN1; SMN2KMT2APOLBRAB9A | |
| Niacinamide SCHEMBL29118199 | 0.78 | ALDH1A1 (0.62) | ALDH1A1NAMPTCYP11B1CYP11B2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148902-A | N-[(optionally substituted phenylamino)carbonyl] pyridine carboxamides and insecticidal use thereof | THE DOW CHEMICAL COMPANY (US) | 1979-04-10 | — | — | US | claimed |