Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | PTGFR | P43088 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | PTGIR | P43119 | 2/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216186 | 1.00 | TBXA2R (0.36) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL5673977 | 0.87 | TBXA2R (0.36) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL5673970 | 0.87 | TBXA2R (0.36) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL5215694 | 0.87 | TBXA2R (0.35) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL5215687 | 0.87 | TBXA2R (0.35) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL5672525 | 0.85 | SLC22A12 (0.40) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL5672522 | 0.85 | SLC22A12 (0.40) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL5672527 | 0.85 | SLC22A12 (0.40) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL5215839 | 0.84 | VDR (0.38) | AGTR1AGTR2 | |
| SCHEMBL27508357 | 0.84 | AGTR1 (0.33) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-B1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | ASTELLAS PHARMA INC (JP) | 2007-10-10 | — | — | EP | disclosed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |