Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.38 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675494 | 0.85 | VDR (0.38) | VDRAGTR1AGTR2GP6 | |
| SCHEMBL5212816 | 0.85 | VDR (0.39) | VDRAGTR1AGTR2IDO1TSHR | |
| SCHEMBL5216186 | 0.84 | TBXA2R (0.36) | AGTR1AGTR2 | |
| SCHEMBL5216178 | 0.84 | TBXA2R (0.36) | AGTR1AGTR2 | |
| SCHEMBL27508357 | 0.83 | AGTR1 (0.33) | AGTR1AGTR2 | |
| SCHEMBL5675559 | 0.79 | AGTR1 (0.40) | AGTR1AGTR2GP6 | |
| SCHEMBL28515127 | 0.76 | AGTR1 (0.52) | VDRAGTR1AGTR2GP6 | |
| SCHEMBL6181231 | 0.72 | VDR (0.52) | VDRTSHR | |
| SCHEMBL8568897 | 0.72 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL28517096 | 0.71 | AGTR1 (0.56) | AGTR1AGTR2GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-B1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | ASTELLAS PHARMA INC (JP) | 2007-10-10 | — | — | EP | disclosed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |