Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216189 | 1.00 | ACHE (0.52) | ACHENPC1RAB9AKMT2AESR2 | |
| SCHEMBL4998559 | 0.93 | ESR2 (0.52) | NPC1RAB9AESR2SMN1; SMN2HPGD | |
| SCHEMBL4998557 | 0.93 | ESR2 (0.52) | NPC1RAB9AESR2SMN1; SMN2HPGD | |
| SCHEMBL10011469 | 0.87 | CES2 (0.52) | SMN1; SMN2HPGDALDH1A1MAPTNPSR1 | |
| SCHEMBL10011472 | 0.87 | CES2 (0.52) | SMN1; SMN2HPGDALDH1A1MAPTNPSR1 | |
| SCHEMBL5001311 | 0.87 | ALDH1A1 (0.41) | ACHENPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL5001309 | 0.87 | ALDH1A1 (0.41) | ACHENPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11759635 | 0.83 | ALDH1A1 (0.51) | ACHENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL14216187 | 0.82 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14215994 | 0.81 | PARP10 (0.46) | NPC1RAB9AESR2SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1842097-A1 | COMPOUNDS HAVING IMPROVED 2-PHOTON ABSORBANCE FOR NONLINEAR APPLICATIONS | Mempile Inc. (US) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006075328-A1 | COMPOUNDS HAVING IMPROVED 2-PHOTON ABSORBANCE FOR NONLINEAR APPLICATIONS | MEMPILE INC. (US) | 2006-07-20 | — | — | WO | disclosed |