SCHEMBL521639

SCHEMBL521639

O=C1C2C3C=CC(C3)C2C(=O)N1c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.79
USP2 O75604 1/20 0.69
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
KDM4E B2RXH2 1/20 0.60
TSHR P16473 3/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2C19 P33261 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
ATM Q13315 1/20 0.58
ALDH1A1 P00352 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
HPGD P15428 1/20 0.56
HTT P42858 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19546873 1.00 POLB (0.79) POLBUSP2MEN1KMT2AKDM4E
SCHEMBL10038046 1.00 POLB (0.79) POLBUSP2MEN1KMT2AKDM4E
SCHEMBL28354072 1.00 POLB (0.79) POLBUSP2MEN1KMT2AKDM4E
SCHEMBL10014710 0.90 USP2 (0.76) POLBUSP2KMT2AKDM4ETSHR
SCHEMBL5512058 0.90 POLB (0.65) POLBUSP2KDM4ETSHRCYP3A4
SCHEMBL4020740 0.87 TSHR (0.66) POLBUSP2MEN1KMT2AKDM4E
SCHEMBL5514868 0.85 KMT2A (0.62) POLBUSP2MEN1KMT2AKDM4E
SCHEMBL4547282 0.85 POLB (0.59) POLBUSP2KDM4ETSHRCYP3A4
SCHEMBL8402141 0.84 POLB (0.63) POLBUSP2MEN1KMT2AKDM4E
SCHEMBL15093017 0.83 USP2 (0.67) POLBUSP2KMT2AKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019649-B Cycloolefin polymer and preparation method thereof 中石油(上海)新材料研究院有限公司 2025-06-03 CN claimed
CN-119019649-A Cycloolefin polymer and preparation method thereof 中石油(上海)新材料研究院有限公司 2024-11-26 CN claimed
US-7655688-B2 Treating nuclear hormone receptor-associated conditions such as cancer and immune disorders; (3a alpha ,4 alpha ,7 alpha ,7a alpha )-2-(3-Chloro-4-hydroxyphenyl)hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione BRISTOL-MYERS SQUIBB COMPANY (US) 2010-02-02 US claimed
US-20060111424-A1 Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function SALVATI MARK E 2006-05-25 US claimed
US-20040087548-A1 Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY 2004-05-06 US claimed
US-4080491-A CATALYST CONTAINS ORGANOMETALLIC COMPOUND AND THE REACTION PRODUCT OF TUNGSTEN OR MOLYBDENUM OXIDE AND A PHOSPHOROUS HALIDE OR OXYHALIDE SHOWA DENKO K.K. (JA) 1978-03-21 US claimed
CN-119019649-B Cycloolefin polymer and preparation method thereof 中石油(上海)新材料研究院有限公司 2025-06-03 CN disclosed
WO-2025100416-A1 CYCLIC OLEFIN RING-OPENED POLYMER, CYCLIC OLEFIN RING-OPENED POLYMER HYDRIDE, RESIN COMPOSITION, AND RESIN MOLDED BODY 日本ゼオン株式会社 2025-05-15 WO disclosed
CN-119462808-A Preparation method of 1 alpha-hydroxy bisnoralcohol 浙江工业大学 2025-02-18 CN disclosed
CN-119019649-A Cycloolefin polymer and preparation method thereof 中石油(上海)新材料研究院有限公司 2024-11-26 CN disclosed
WO-2024130537-A1 ELECTROLYTE, ELECTROCHEMICAL APPARATUS AND ELECTRONIC APPARATUS 东莞新能源科技有限公司 2024-06-27 WO disclosed
WO-2024130535-A1 ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE 东莞新能源科技有限公司 2024-06-27 WO disclosed
CN-111538209-B Photosensitive resin composition, organic EL element partition wall, and organic EL element 日保丽公司 2024-05-14 CN disclosed
US-4105608-A HIGH IMPACT COMPOSITION OF RING-OPENING POLYMERIZATION PRODUCT SHOWA DENKO K.K. (JP) 1978-08-08 US disclosed
US-4080491-A CATALYST CONTAINS ORGANOMETALLIC COMPOUND AND THE REACTION PRODUCT OF TUNGSTEN OR MOLYBDENUM OXIDE AND A PHOSPHOROUS HALIDE OR OXYHALIDE SHOWA DENKO K.K. (JA) 1978-03-21 US disclosed
US-4068063-A Catalyst composition for ring-opening polymerization of norbornene derivatives and process for polymerizing same JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1978-01-10 US disclosed
US-4059561-A AND A HALOGEN COMPOUND SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-11-22 US disclosed
US-4028482-A LOW VISCOSITY POLYALKENAMER SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-06-07 US disclosed
US-3991139-A NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-11-09 US disclosed
US-3959234-A CATALYSTS OF ORGANOALUMINUM COMPOUNDS AND A TUNGSTEN OR MOLYBDENUM COMPOUND, RING-OPENING SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087548-A1 Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function NCOA1, ESRRA, NR5A1 POLB 3096/4885USP2 1946/4885MEN1 1676/4885
US-20060111424-A1 Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function NCOA1, ESRRA, NR5A1 POLB 3096/4885USP2 1946/4885MEN1 1676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.