Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28347955 | 0.95 | USP2 (0.61) | USP2TSHRCYP3A4CYP2C19NPSR1 | |
| SCHEMBL10014710 | 0.92 | USP2 (0.76) | USP2TSHRCYP3A4CYP2C19NPSR1 | |
| SCHEMBL2240063 | 0.91 | ALDH1A1 (0.74) | USP2TSHRCYP3A4CYP2C19NPSR1 | |
| SCHEMBL5958827 | 0.84 | TSHR (0.69) | USP2TSHRCYP3A4CYP2C19NPSR1 | |
| SCHEMBL3190265 | 0.84 | CA1 (0.65) | USP2TSHRCYP3A4CYP2C19NPSR1 | |
| SCHEMBL3201450 | 0.84 | CA1 (0.65) | USP2TSHRCYP3A4CYP2C19NPSR1 | |
| SCHEMBL3190257 | 0.84 | CA1 (0.65) | USP2TSHRCYP3A4CYP2C19NPSR1 | |
| SCHEMBL4590679 | 0.84 | CA1 (0.65) | USP2TSHRCYP3A4CYP2C19NPSR1 | |
| SCHEMBL5922804 | 0.84 | USP2 (0.65) | USP2TSHRCYP3A4CYP2C19NPSR1 | |
| SCHEMBL3201440 | 0.84 | CA1 (0.65) | USP2TSHRCYP3A4CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023340-B2 | Wnt inhibitors for human stem cell differentiation | CHEMREGEN, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20130177535-A1 | WNT INHIBITORS FOR HUMAN STEM CELL DIFFERENTIATION | CHEMREGEN, INC | 2013-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130177535-A1 | WNT INHIBITORS FOR HUMAN STEM CELL DIFFERENTIATION | WNT3A, WNT1, WNT3 | USP2 3943/4885TSHR 3660/4885CYP3A4 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.