Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494374 | 0.88 | KMT2A (0.51) | KMT2ASMN1; SMN2HSD17B10POLBMEN1 | |
| SCHEMBL4020740 | 0.87 | TSHR (0.66) | KMT2ASMN1; SMN2POLBMEN1TSHR | |
| SCHEMBL5512058 | 0.86 | POLB (0.65) | SMN1; SMN2POLBTSHRCYP3A4CYP2C19 | |
| SCHEMBL19546873 | 0.85 | POLB (0.79) | KMT2ASMN1; SMN2POLBMEN1TSHR | |
| SCHEMBL10038046 | 0.85 | POLB (0.79) | KMT2ASMN1; SMN2POLBMEN1TSHR | |
| SCHEMBL28354072 | 0.85 | POLB (0.79) | KMT2ASMN1; SMN2POLBMEN1TSHR | |
| SCHEMBL521639 | 0.85 | POLB (0.79) | KMT2ASMN1; SMN2POLBMEN1TSHR | |
| SCHEMBL4592297 | 0.81 | CA1 (0.60) | POLBTSHRCYP3A4CYP2C19NPSR1 | |
| SCHEMBL3189633 | 0.81 | CA1 (0.60) | POLBTSHRCYP3A4CYP2C19NPSR1 | |
| SCHEMBL3189623 | 0.81 | CA1 (0.60) | POLBTSHRCYP3A4CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-20060189771-A1 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2006-08-24 | — | — | US | disclosed |
| US-20060041092-A1 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2006-02-23 | — | — | US | disclosed |
| EP-1561766-A1 | RING-OPENED POLYNORBORNENES | JSR Corporation (JP) | 2005-08-10 | — | — | EP | disclosed |