Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5254076 | 0.83 | ASPH (0.32) | ASPH | |
| SCHEMBL5215635 | 0.80 | KDM4E (0.38) | ASPH | |
| SCHEMBL8008655 | 0.77 | SSTR4 (0.42) | — | |
| SCHEMBL2355586 | 0.74 | ASPH (0.38) | ASPHRXRARXRBRXRG | |
| SCHEMBL667777 | 0.71 | PPARG (0.51) | MAOBRXRARXRBRXRGPPARG | |
| SCHEMBL4923887 | 0.69 | ASPH (0.56) | ASPH | |
| SCHEMBL5502758 | 0.69 | DAO (0.32) | MAOBRXRARXRBRXRGPPARG | |
| SCHEMBL11435438 | 0.67 | NPC1 (0.31) | — | |
| SCHEMBL10934851 | 0.67 | MRGPRX4 (0.41) | MAOBRXRARXRBRXRGPPARG | |
| SCHEMBL17644333 | 0.66 | MGLL (0.33) | ASPHL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763303-A1 | SUBSTITUTED PYRIDAZINE CARBOXAMIDES AND DERIVATIVES THEREOF | Bayer CropScience Aktiengesellschaft (DE) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006000333-A1 | SUBSTITUTED PYRIDAZINE CARBOXAMIDES AND DERIVATIVES THEREOF | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-01-05 | — | — | WO | disclosed |