Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 1.00 |
| ▸ | BCHE | P06276 | 2/20 | 1.00 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.88 |
| ▸ | MAOA | P21397 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.66 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.66 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.66 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.66 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.66 |
| ▸ | ACHE | P22303 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.66 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.66 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.65 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3012785 | 1.00 | MAOB (1.00) | MAOBBCHECYP1B1MAOAMAPT | |
| SCHEMBL11803175 | 1.00 | MAOB (1.00) | MAOBBCHECYP1B1MAOAMAPT | |
| SCHEMBL521695 | 0.94 | CYP1B1 (1.00) | MAOBBCHECYP1B1MAOAMAPT | |
| SCHEMBL3082127 | 0.94 | CYP1B1 (1.00) | MAOBBCHECYP1B1MAOAMAPT | |
| SCHEMBL6733854 | 0.92 | MAOB (0.85) | MAOBBCHECYP1B1MAOAMAPT | |
| SCHEMBL6733848 | 0.92 | MAOB (0.85) | MAOBBCHECYP1B1MAOAMAPT | |
| SCHEMBL9241211 | 0.89 | MAOB (0.81) | MAOBBCHECYP1B1MAOAMAPT | |
| SCHEMBL9136943 | 0.89 | MAOB (0.80) | MAOBBCHECYP1B1MAOAMAPT | |
| SCHEMBL9136940 | 0.89 | MAOB (0.80) | MAOBBCHECYP1B1MAOAMAPT | |
| SCHEMBL7454702 | 0.86 | PTPN1 (0.82) | MAOBBCHECYP1B1MAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023027630-A9 | A FLOW REACTOR, METHODS OF FABRICATION AND REACTIONS THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-07-27 | — | — | WO | claimed |
| WO-2023027630-A2 | A FLOW REACTOR, METHODS OF FABRICATION AND REACTIONS THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-03-02 | — | — | WO | claimed |
| CN-104030984-B | A kind of preparation method of pyrazole derivatives | 甘肃农业大学 | 2016-07-13 | — | — | CN | claimed |
| CN-104030870-B | A kind of preparation method of beta-cyano ketone | NORTHWEST NORMAL UNIVERSITY (CN) | 2015-10-28 | — | — | CN | claimed |
| CN-104030984-A | Method for preparing pyrazole derivative | UNIV NORTHWEST NORMAL | 2014-09-10 | — | — | CN | claimed |
| CN-104030870-A | Method for preparing beta-cyan ketone | UNIV NORTHWEST NORMAL | 2014-09-10 | — | — | CN | claimed |
| US-20120029197-A1 | Method for Preparing Sulfur-Containing Compounds | THE ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2012-02-02 | — | — | US | claimed |
| EP-2376444-A1 | A METHOD FOR PREPARING SULFUR-CONTAINING COMPOUNDS | The Royal College of Surgeons in Ireland (IE) | 2011-10-19 | — | — | EP | claimed |
| WO-2010066450-A1 | A METHOD FOR PREPARING SULFUR-CONTAINING COMPOUNDS | THE ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2010-06-17 | — | — | WO | claimed |
| US-7732534-B2 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION (JP) | 2010-06-08 | — | — | US | claimed |
| US-20080051519-A1 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION (JP) | 2008-02-28 | — | — | US | claimed |
| US-20080051552-A1 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION | 2008-02-28 | — | — | US | claimed |
| CN-119330973-A | Spiro indolone pyrrolidine compound and preparation method and application thereof | 贵州省天然产物研究中心 | 2025-01-21 | — | — | CN | disclosed |
| CN-119330973-A | Spiro indolone pyrrolidine compound and preparation method and application thereof | 贵州省天然产物研究中心 | 2025-01-21 | — | — | CN | disclosed |
| CN-114524829-B | Preparation method of imidazo [2,1-b ] thiazole derivative | 新疆大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-115368268-B | Method for efficiently preparing azo compound and application thereof | 大连理工大学 | 2023-11-17 | — | — | CN | disclosed |
| US-4857527-A | HYPOTENSIVE, ANTISCHEMIC AGENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| US-4831030-A | FOR CEREBROVASCULAR DISEASES; HYPERTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0228845-A2 | N-containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-07-15 | — | — | EP | disclosed |
| US-3989708-A | HYPOTENSIVE, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029197-A1 | Method for Preparing Sulfur-Containing Compounds | SULT1E1, SULT1A1, TST | MAOB 1192/4885BCHE 4699/4885CYP1B1 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.